# RC29 source and coverage record

Checked September 25, 2026. These sources support the identified changes; they do not validate every inherited calculator or the complete medication profile.

| Component | Primary source | Scope |
|---|---|---|
| Lantus | https://products.sanofi.us/lantus/lantus.html | Package/device, priming and storage |
| Tresiba | https://www.novo-pi.com/tresiba.pdf | Package, device increments/maximums, priming and storage |
| Toujeo | https://products.sanofi.us/toujeo/toujeo.html | SoloStar/Max device and storage details |
| Humalog | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c8ecbd7a-0e22-4fc7-a503-faa58c1b6f3f | KwikPen/Junior and vial package/device/storage details |
| Levofloxacin renal matrix | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b001d60e-b8fb-54ff-e053-2a95a90a2970 | Adult oral renal table 3; six non-dialysis branches |
| Metformin metric | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a944a167-e3ac-4084-af1c-22b48713471c | Indexed eGFR thresholds in an ER label; verify exact formulation |
| Renal metric context | https://www.niddk.nih.gov/research-funding/research-programs/kidney-clinical-research-epidemiology/laboratory/ckd-drug-dosing-providers | Kidney estimates and BSA-indexed values in drug dosing |

The packaged legacy renal thresholds and 19 targeted interaction pairs are inherited screening content. They are not a licensed comprehensive interaction database or newly validated dose monographs. Each local dose rule stores its own source/version and requires matching context. No institution approval is fabricated.

The new insulin model has synthetic arithmetic tests, not payer claim-adjudication validation. Real de-identified EHR images and approved facility dosing/preparation tables were not supplied. Replay and local-rule maintenance tools support adding that validation and content.

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## RC30 medication reconciliation workflow

Workflow reference: AHRQ MATCH Toolkit, Introduction and Table 3 (reviewed September 25, 2026):
- https://www.ahrq.gov/patient-safety/settings/hospital/match/intro.html
- https://www.ahrq.gov/patient-safety/settings/hospital/match/table-3.html

Compare the home regimen with acute orders, identify discrepancies, then document whether the difference is intentional or needs clarification. Profile matching is software assistance; source completeness, actual home use, intent and clinical appropriateness remain pharmacist determinations. No new drug equivalence or dosing rules were introduced by RC30.
